SARS-CoV-2 Mpro-IN-31 - CAS 870153-73-4

SARS-CoV-2 Mpro-IN-31 (Compound 18) is an inhibitor of SARS-CoV-2 MPro with an IC50 of 11 nM. Additionally, this compound effectively inhibits the enzymatic activity of the cysteine proteases cathepsin B and cathepsin L, with IC50 values of 24 nM and 1.8 nM, respectively.

SARS-CoV

Microbiology/Virology

870076

C31H34Cl2N4O7

645.53

O(C)C1=C2C(NC(C(N[C@H](C(N[C@@H](C[C@H]3C(=O)NCC3)C(COC(=O)C4=C(Cl)C=CC=C4Cl)=O)=O)CC(C)C)=O)=C2)=CC=C1

-20°C

Ice Packs

Small Compound