SARS-CoV-2 Mpro-IN-44 - CAS 3020713-53-2

SARS-CoV-2 Mpro-IN-44 (Compound 25) is a broad-spectrum inhibitor of the main protease (Mpro) for coronaviruses. It exhibits inhibitory activity against several high-risk coronaviruses, including SARS-CoV-2 and PEDV, with an IC50 of less than 0.6 μM. The broad inhibition of coronaviruses by SARS-CoV-2 Mpro-IN-44 is achieved through enhanced interaction with conserved sites of Mpro. This compound is a potential candidate for the development of antiviral drugs against coronaviruses.

Virus Protease, SARS-CoV

Microbiology/Virology

3020658

C29H19Cl2FN8O4S

665.48

C(N1\C(=N\C2=CC=3C(C=C2Cl)=NN(C)C3)\NC(=O)N(CC=4C(=O)NC=CC4)C1=O)C5=C(OC=6SC(C#N)=CC6)C=C(F)C(Cl)=C5

-20°C

Ice Packs

Small Compound