SARS-CoV-2 Mpro-IN-9 - CAS 2754370-99-3

SARS-CoV-2 Mpro-IN-9 (compound c7), a nonpeptidic, noncovalent inhibitor of SARS-CoV-2 main protease (Mpro), exhibits potent inhibitory action (IC50 = 0.085 μM) and improved physicochemical and drug metabolism and pharmacokinetics (DMPK) properties. It effectively suppresses viral replication in SARS-CoV-2-infected Vero E6 cells (EC50 = 1.10 μM) and demonstrates low cytotoxicity (CC50 > 50 μM) [1].

SARS-CoV

Microbiology/Virology

2754268

0.9989

C20H14N2O4

346.34

O=C1C=2C(N=C(C=3C=CC=CC3)N1C=4C=CC=CC4)=CC(O)=C(O)C2O

-20°C

Ice Packs

Small Compound