SARS-CoV MPro-IN-1 - CAS 2413716-71-7

MProinhibitor 11b is an inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (MPro; IC50= 0.04 μM in a TR-FRET assay) .1It reduces viral yield in the culture supernatant of SARS-CoV-2-infected Vero E6 cells (EC50= 0.72 μM) . MProinhibitor 11b also reduces viral RNA copy numbers in the same model when used at concentrations ranging from 1.85 to 50 μM.

Others, SARS-CoV

Microbiology/Virology, Others

2413638

C25H25FN4O4

464.49

C(N[C@@H](CC1=CC(F)=CC=C1)C(N[C@@H](C[C@H]2C(=O)NCC2)C=O)=O)(=O)C3=CC=4C(N3)=CC=CC4

-20°C

Ice Packs

Small Compound