Saterinone - CAS 102669-89-6

Saterinone is a potent and selective phosphodiesterase III inhibitor and a potent antagonist of the vascular α-1-adrenoceptor. Saterinone has vasodilatory properties and can be used in the acute treatment of chronic heart failure. Saterinone inhibited crude cAMP phosphodiesterase (PDE) activity in guinea pig right ventricular homogenates The ic50 value is 2.3 x 10 (-5) mol/l.

PDE, Adrenergic Receptor

Neuroscience, GPCR/G Protein, Metabolism

102574

>99.99%

C27H30N4O4

474.55

CC1=C(C=C(C#N)C(=O)N1)C2=CC=C(OCC(CN3CCN(CC3)C4=C(OC)C=CC=C4)O)C=C2

-20°C

Ice Packs

Small Compound