Molfinity
Sauchinone - CAS 177931-17-8
Sauchinone - CAS 177931-17-8
SKU:MF-0012089-01
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Product Details
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Bioactivity
1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative stress in vivo and in vitro. 3. Sauchinone diminishes LPS-induced neutrophil activation and acute lung injury. 4. Sauchinone-induced HO-1 expression plays a key role in the vascular protective effects of Sauchinone in HUVEC. 5. Sauchinone protects skin keratinocytes through inhibition of extracellular signal-regulated kinase, c-Jun N-terminal kinase, and p38 MAPK signaling via upregulation of oxidative defense enzymes.
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Target
ERK, NF-κB, p38 MAPK
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Related Pathways
NF-κB, MAPK
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CAS Number
177931-17-8
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Purity
>99.99%
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Molecular Formula
C20H20O6
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Molecular Weight
356.37
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SMILES
C[C@@H]1C[C@@H]2[C@H]3[C@@H]([C@H]1C)c1cc4OCOc4cc1O[C@]31OCOC1=CC2=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product