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Molfinity

Sauchinone - CAS 177931-17-8

Sauchinone - CAS 177931-17-8

SKU:MF-0012089-01

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  • Bioactivity

    1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative stress in vivo and in vitro. 3. Sauchinone diminishes LPS-induced neutrophil activation and acute lung injury. 4. Sauchinone-induced HO-1 expression plays a key role in the vascular protective effects of Sauchinone in HUVEC. 5. Sauchinone protects skin keratinocytes through inhibition of extracellular signal-regulated kinase, c-Jun N-terminal kinase, and p38 MAPK signaling via upregulation of oxidative defense enzymes.

  • Target

    ERK, NF-κB, p38 MAPK

  • Related Pathways

    NF-κB, MAPK

  • CAS Number

    177931-17-8

  • Purity

    >99.99%

  • Molecular Formula

    C20H20O6

  • Molecular Weight

    356.37

  • SMILES

    C[C@@H]1C[C@@H]2[C@H]3[C@@H]([C@H]1C)c1cc4OCOc4cc1O[C@]31OCOC1=CC2=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product