SB-1436 - CAS 2925298-08-2

SB-1436 is a Cholinesterase (ChE) inhibitor that inhibits acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and recombinant human acetylcholinesterase (rHuAChE) with IC50 values of 0.176, 0.37, and 0.08 μM, respectively. It inhibits AChE and BChE in a non-competitive manner with Ki values of 0.046 and 0.115 μM, respectively. Additionally, SB-1436 significantly prevents the self-aggregation of Aβ and can be used for neurological disease research [1].

Cholinesterase (ChE)

Neuroscience

2925298-08-2

C25H21ClFNO

405.89

C(=C/C=1C=C[N+](CC2=CC=C(F)C=C2)=CC1)\C3=CC4=C(C=C(OC)C=C4)C=C3.[Cl-]

-20°C

Ice Packs

Small Compound