SB-218078 - CAS 135897-06-2

SB-218078 is less potently inhibits Cdc2 (IC50: 250 nM) and PKC (IC50: 1000 nM) . SB-218078 is a potent, ATP-competitive, and cell-permeable checkpoint kinase 1 inhibitor that inhibits Chk1 phosphorylation of cdc25C (IC50: 15 nM) .

PKC, Apoptosis, Chk, CDK

Chromatin/Epigenetic, Apoptosis, Cell Cycle/Checkpoint, Cytoskeletal Signaling

135897-06-2

C24H15N3O3

393.39

O=C1NC(=O)c2c1c1c3ccccc3n3C4CCC(O4)n4c5ccccc5c2c4c13

-20°C

Ice Packs

Small Compound