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SB-747651A - CAS 607372-46-3
SB-747651A - CAS 607372-46-3
SKU:MF-0041418-01
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$1,515.42 USD
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$1,515.42 USD
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Product Details
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Bioactivity
SB-747651A is a potent, ATP-competitive inhibitor of mitogen- and stress-activated kinase 1 (MSK1, IC50 = 11 nM) . It targets the N-terminal kinase domain. SB-747651A inhibits MSK1, MSK2, PKA, PKB, RSK and p70S6K activity in cells.
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Target
Others, p38 MAPK
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Related Pathways
MAPK, Others
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CAS Number
607323
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Molecular Formula
C16H22N8O
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Molecular Weight
342.4
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SMILES
C(C)N1C=2C(N=C1C=3C(N)=NON3)=CN=CC2CNC4CCNCC4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound