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SB-747651A Dihydrochloride - CAS 1781882-72-1

SB-747651A Dihydrochloride - CAS 1781882-72-1

MF-0018837-01

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Product Details

  • Bioactivity

    SB-747651A dihydrochloride is a chemical compound that serves as an ATP-competitive inhibitor for mitogen- and stress-activated kinase 1 (MSK1), featuring an IC50 of 11 nM. Additionally, this compound effectively inhibits PRK2, RSK1, p70S6K, and ROCK-II, showcasing its potential in inflammation research [1].

  • Target

    ROCK, p38 MAPK

  • Related Pathways

    Cell Cycle/Checkpoint, MAPK, Stem Cells, Cytoskeletal Signaling

  • CAS Number

    1781809

  • Purity

    0.9805

  • Molecular Formula

    C16H24Cl2N8O

  • Molecular Weight

    415.32

  • SMILES

    Cl.Cl.CCn1c(nc2cncc(CNC3CCNCC3)c12)-c1nonc1N

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound