SCH-23390 - CAS 87075-17-0

SCH-23390 is a dopamine D1-like receptor antagonist (with Ki values of 0.2 nM for the D1 receptor subtype and 0.3 nM for the D5 receptor subtype) . It reduces the latency of lever pressing behavior induced by cocaine in rats. Additionally, SCH-23390 can eliminate generalized seizures triggered by the chemical convulsants pilocarpine and soman, making it useful for studies on neurodegenerative diseases related to the dopamine system.

Dopamine Receptor

Neuroscience, GPCR/G Protein

87058

C17H18ClNO

287.784

OC=1C=C2[C@H](CN(C)CCC2=CC1Cl)C3=CC=CC=C3

-20°C

Ice Packs

Small Compound