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SCH900776 (S-isomer) - CAS 891494-64-7

SCH900776 (S-isomer) - CAS 891494-64-7

SKU:MF-0012586-01

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  • Bioactivity

    SCH900776 S-isomer (MK-8776 S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM) . It also inhibitors Chk2 (IC50: 1500 nM) and cyclin-dependent kinase CDK2 (IC50: 160 nM) .

  • Target

    CDK, Chk, Others

  • Related Pathways

    Cell Cycle/Checkpoint, Others

  • CAS Number

    891494-64-7

  • Purity

    0.9995

  • Molecular Formula

    C15H18BrN7

  • Molecular Weight

    376.25

  • SMILES

    Cn1cc(cn1)-c1cnn2c(N)c(Br)c(nc12)[C@H]1CCCNC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound