Sclerotiorin - CAS 549-23-5

Sclerotiorin is a natural product isolated primarily from Penicillium species. It inhibits soybean lipoxygenase-1 with an IC50 value of 4.2 μM. Sclerotiorin also exhibits a number of other activities including inhibition of cholesterol ester transfer protein (IC50 = 19.4 μM), , inhibition of Grb2-Shc interaction (IC50 = 22 μM), , and antagonism of endothelin receptors (IC50 = 114 and 152 μM for human ETA and ETB, respectively) .

Others, Lipoxygenase, Antifungal

Metabolism, Microbiology/Virology, Others

521

C21H23ClO5

390.86

O=C1C=2C(=C(Cl)C(=O)[C@@]1(OC(C)=O)C)C=C(/C=C/C(=C/[C@H](CC)C)/C)OC2

-20°C

Ice Packs

Natural Product