SCNH240 - CAS 1357746-77-0

SCNH240 (2-Fluoro-N-[3- (3-thienyl) -5-isoxazolyl]benzenesulfonamide) is a potential and selective Rv1625c/Cya activator with good cell permeability and oral activity, IC90=1.24 μM in cholesterol-supplemented 7H12 medium against Mycobacterium tuberculosis (Mtb) H37Rv strain, and inhibition of CYP2C19, CYP2C9 and hERG channels.

Potassium Channel, Cytochromes P450, Antibacterial

Microbiology/Virology, Membrane transporter/Ion channel, Metabolism

1357669

0.9982

C13H9FN2O3S2

324.35

O=S(=O)(NC=1ON=C(C1)C2=CSC=C2)C=3C=CC=CC3F

-20°C

Ice Packs

Small Compound