SDU-071 - CAS 3036109-10-8

SDU-071 is an orally active BRD4-p53 inhibitor, inhibiting the proliferation of MDA-MB-231 cells, blocking the interaction between BRD4 and the tumor suppressor p53, downregulating the expression of BRD4-targeted genes, thereby inhibiting cell proliferation, migration, and invasion, and inducing cell cycle arrest and apoptosis. SDU-071 is used for research on triple-negative breast cancer.

Apoptosis, Epigenetic Reader Domain

Apoptosis, Chromatin/Epigenetic

3036091

0.9954

C28H25N3O2

435.52

COC(C=C1)=CC=C1NCC(C=C2NC3=CC=C(OC)C=C3)=NC4=C2C=CC5=C4C=CC=C5

-20°C

Ice Packs

Small Compound