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γ-Secretase modulator 11 hydrochloride - CAS 2434630-30-3
γ-Secretase modulator 11 hydrochloride - CAS 2434630-30-3
SKU:MF-0038597-01
Regular price
$1,383.80 USD
Regular price
Sale price
$1,383.80 USD
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Product Details
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Bioactivity
γ-Secretase modulator 11 hydrochloride is a potent, orally active γ-secretase modulator (IC50: 0.029 μM) . γ-Secretase modulator 11 hydrochloride significantly reduces brain Aβ42 levels and rescues the cognitive deficits exhibited by AD model mice. γ-Secretase modulator 11 hydrochloride has shown research potential in Alzheimer's disease.
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Target
Others, Gamma-secretase
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Related Pathways
Neuroscience, Stem Cells, Others, Proteases/Proteasome
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CAS Number
2434597
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Molecular Formula
C28H23ClF2N4O2
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Molecular Weight
520.96
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SMILES
Cl.CNC(=O)c1ccc(cn1)-c1c(C)nc2c(OCc3ccc(cc3F)-c3ccc(F)cc3)cccn12
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound