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Segigratinib hydrochloride - CAS 2847066-15-1

Segigratinib hydrochloride - CAS 2847066-15-1

MF-0122078-01

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Product Details

  • Bioactivity

    Segigratinib hydrochloride (3D185) is an effective inhibitor of FGFR1/2/3 and CSF-1R, exhibiting IC50 values of 0.5, 1.3, 3.6, and 3.8 nM for FGFR1, FGFR2, FGFR3, and CSF-1R, respectively. This compound possesses anti-tumor activity.

  • CAS Number

    2847066-15-1

  • Molecular Formula

    C27H29Cl3N6O3

  • Molecular Weight

    591.92

  • SMILES

    Cl.O=C(NC1=NNC=2N=C(C=CC12)C=3C(Cl)=C(OC)C=C(OC)C3Cl)C4=CC=C(C=C4)N5CCNC(C)(C)C5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound