SEH/HDAC6-IN-1 - CAS 2847838-67-7

SEH/HDAC6-IN-1 (compound M9) serves as a selective, orally active dual inhibitor targeting both sEH and HDAC6. It demonstrates IC50 values of 2 nM for human sEH, 0.72 nM for murine sEH, and 5 nM for HDAC6. Notably, sEH/HDAC6-IN-1 exhibits analgesic and anti-inflammatory effects [1].

Epoxide Hydrolase, HDAC

Chromatin/Epigenetic, DNA Damage/DNA Repair, Metabolism

2847838-67-7

C27H40N4O4

484.63

N(C(NC1=CC=C(C(NCCCCCCC(NO)=O)=O)C=C1)=O)C23CC4(C)CC(C)(C2)CC(C3)C4

-20°C

Ice Packs

Small Compound