SEH-IN-21 - CAS 3084814-46-7

SEH-IN-21 is an orally active inhibitor of sEH, exhibiting IC50 values of 0.1 nM for both hsEH and msEH. It significantly suppresses the NF-κB signaling pathway. sEH-IN-21 demonstrates potent anti-inflammatory activity by reducing IL-6 and TNF-α release and maintaining intestinal barrier integrity. It is applicable in research on inflammatory bowel disease (IBD) .

Epoxide Hydrolase, Interleukin, NF-κB, TNF

Metabolism, Apoptosis, Immunology/Inflammation, NF-κB

3084761

C30H40N4O5S

568.73

N(C(N[C@H]1CC[C@H](NC2=C(NS(=O)(=O)C3=CC=C(C)C=C3)C(=O)C2=O)CC1)=O)C45CC6(C)CC(C)(C4)CC(C5)C6

-20°C

Ice Packs

Small Compound