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Selumetinib - CAS 606143-52-6

Selumetinib - CAS 606143-52-6

MF-0005146-01

$45.13 USD
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Product Details

  • Bioactivity

    Selumetinib (AZD6244) is a MEK1/2 inhibitor that inhibits MEK1 (IC50=14 nM) with potent selectivity and is non-ATP-competitive. Selumetinib has antitumor activity and is used for the treatment of neurofibromatosis type 1 (NF1) .

  • Target

    ERK, MEK, Apoptosis

  • Related Pathways

    MAPK, Apoptosis

  • CAS Number

    606143-52-6

  • Purity

    0.999

  • Molecular Formula

    C17H15BrClFN4O3

  • Molecular Weight

    457.68

  • SMILES

    CN1C=NC2=C(F)C(NC3=CC=C(Br)C=C3Cl)=C(C=C12)C(=O)NOCCO

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound