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Semagacestat - CAS 425386-60-3
Semagacestat - CAS 425386-60-3
SKU:MF-0012427-01
Regular price
$35.41 USD
Regular price
$22.10 USD
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$35.41 USD
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Product Details
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Bioactivity
Semagacestat (LY450139) (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM) .
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Target
Gamma-secretase, Beta Amyloid
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Related Pathways
Proteases/Proteasome, Stem Cells, Neuroscience
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CAS Number
425386-60-3
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Purity
0.999
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Molecular Formula
C19H27N3O4
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Molecular Weight
361.44
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SMILES
CC(C)[C@H](O)C(=O)N[C@@H](C)C(=O)N[C@H]1c2ccccc2CCN(C)C1=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound