Seribantumab - CAS 1334296-12-6

Seribantumab (MM 121) is a humanized monoclonal antibody targeting HER3, inhibiting NRG1-induced growth in MCF-7 cells and patient-derived breast and lung cancer cells harboring NRG1 fusions or amplifications. It also induces apoptosis in MDA-MB-175-VII and LUAD-0061AS3 cells.

EGFR, HER, Apoptosis

Tyrosine Kinase/Adaptors, Angiogenesis, Apoptosis, JAK/STAT signaling

1334278

0.9626

-20°C

Ice Packs

Inhibitory Antibodies