Molfinity
Serratenediol - CAS 2239-24-9
Serratenediol - CAS 2239-24-9
SKU:MF-0039715
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Product Details
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Bioactivity
Serratenediol demonstrates strong inhibitory effects on the Epstein-Barr virus early antigen (EBV-EA) activation without showing any cytotoxicity, its effects being stronger than that of a representative control, oleanolic acid. Serratenediol can promote the proliferation rate, alkaline phosphate (ALP) activity and some osteogenic gene expression of osteoblasts. Serratenediol also has significant and dose-dependent growth inhibitory effects on HL-60 cells via regulating the ratio of Bax/Bcl-xL.
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Target
Caspase, Bcl-2 Family, PARP
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Related Pathways
DNA Damage/DNA Repair, Proteases/Proteasome, Chromatin/Epigenetic, Apoptosis
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CAS Number
2206
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Molecular Formula
C30H50O2
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Molecular Weight
442.72
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SMILES
CC1(C)[C@@H](O)CC[C@@]2(C)[C@H]1CC[C@@]1(C)CC3=CC[C@H]4C(C)(C)[C@@H](O)CC[C@]4(C)[C@H]3CC[C@H]21
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product