Sesamol - CAS 533-31-3

Sesamol (1,3-Benzodioxol-5-ol) could decrease lung inflammation and lipopolysaccharide (LPS) -induced lung injury in rats. Sesamol ameliorates inflammatory and oxidative damage by upregulating AMPK activation and Nrf2 signaling and blocking the NF-κB and MAPK signaling pathways and inhibits melanin biosynthesis by down-regulating tyrosinase activity and melanin production via regulation of gene expression of melanogenesis-related proteins through modulation of MITF activity, which promotes phosphorylation of p38 and JNK in melan-a cells.

AMPK, Apoptosis

PI3K/Akt/mTOR signaling, Apoptosis, Chromatin/Epigenetic

499

>99.99%

C7H6O3

138.12

OC1=CC2=C(OCO2)C=C1

-20°C

Ice Packs

Natural Product