Setrobuvir - CAS 1071517-39-9

Setrobuvir (ANA-598) is an orally active non-nucleoside HCV NS5B polymerase inhibitor with inhibitory effects on de novo RNA synthesis and primer extension with IC50s between 4 and 5 nM. setrobuvir shows good binding affinity for SARS-CoV-2 RdRp and induces inhibition of RdRp.

DNA/RNA Synthesis, SARS-CoV, HCV Protease

Microbiology/Virology, Proteases/Proteasome, DNA Damage/DNA Repair, Cell Cycle/Checkpoint

1071469

>99.99%

C25H25FN4O6S2

560.62

C(N1[C@@]2([C@@]([C@@]3(C[C@]2(CC3)[H])[H])(C(O)=C(C1=O)C=4NC=5C(S(=O)(=O)N4)=CC(NS(C)(=O)=O)=CC5)[H])[H])C6=CC=C(F)C=C6

-20°C

Ice Packs

Small Compound