SG2057 - CAS 260417-62-7

SG2057 (DRG16), a potent antitumor agent, is a pyrrolobenzodiazepine (PBD) dimer connected by a pentyldioxy linkage. This compound selectively binds to the minor groove of DNA, forming both interstrand and intrastrand cross-linked adducts, contributing to its high antitumor activity.

DNA Alkylator/Crosslinker, ADC Cytotoxin

DNA Damage/DNA Repair, Antibody-drug Conjugate/ADC Related

260348

C33H36N4O6

584.66

O=C1C=2C(=CC(OCCCCCOC3=C(OC)C=C4C(=C3)N=C[C@]5(N(C4=O)CC(=C)C5)[H])=C(OC)C2)N=C[C@]6(N1CC(=C)C6)[H]

-20°C

Ice Packs

Small Compound