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SG3199 - CAS 1595275-71-0
SG3199 - CAS 1595275-71-0
SKU:MF-0040313
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Product Details
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Bioactivity
SG3199 is a PBD dimer which binds in the minor groove of DNA, and forms covalent DNA interstrand cross-links in naked linear plasmid DNA. SG3199 is potently cytotoxic against a panel of human solid tumour and haematological cancer cell lines.
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Target
ADC Cytotoxin, DNA Alkylator/Crosslinker
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Related Pathways
Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair
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CAS Number
1595204
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Molecular Formula
C33H36N4O6
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Molecular Weight
584.66
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SMILES
[H][C@@]12CC(C)=CN1C(=O)c1cc(OC)c(OCCCCCOc3cc4N=C[C@]5([H])CC(C)=CN5C(=O)c4cc3OC)cc1N=C2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound