SGK1-IN-3 - CAS 2891696-18-5

SGK1-IN-3 is a potent, orally active SGK1 inhibitor. Among them, the serine/threonine kinase SGK1, an activator of the β-linked protein pathway and a powerful stimulator of cartilage degradation, has been found to be upregulated under genomic control in diseased osteoarthritic cartilage. SGK1-IN-3 shows research potential in osteoarthritis.

SGK, Others

Metabolism, Others

2891673

C23H20Cl2N6O3S

531.414

C(N[C@@H]1CCNC1)(=O)C2=C3C(=NC(=C2)C4=CC=C(NS(=O)(=O)C5=C(Cl)C(Cl)=CC=C5)C=C4)NN=C3

-20°C

Ice Packs

Small Compound