(+) -Shikonin - CAS 517-89-5

(+) -Shikonin (Anchusa acid) is a natural product, a TMEM16A chloride channel inhibitor (IC50=6.5 μM) and selective PKM2 inhibitor. (+) - Shikonin exhibits antitumor, anti-inflammatory and wound healing activities.

PKM, HIV Protease, NF-κB, Chloride channel, AIM2, TNF

Apoptosis, Metabolism, Membrane transporter/Ion channel, Immunology/Inflammation, NF-κB, Proteases/Proteasome, Microbiology/Virology

423

0.999

C16H16O5

288.3

CC(C)=CC[C@@H](O)C1=CC(=O)c2c(O)ccc(O)c2C1=O

-20°C

Ice Packs

Natural Product