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Molfinity

ShK-Dap22 - CAS 220384-25-8

ShK-Dap22 - CAS 220384-25-8

SKU:MF-0153906

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  • Bioactivity

    Extremely potent KV1.3 channel blocker (Kd = 23 pM for mKV1.3 currents) . Selective for KV1.3 over other mammalian potassium channels (IC50 values are 23, 1800, 10500, 37000 and 39000 pM for mKV1.3, mKV1.1, hKV1.6, mKV1.4 and rKV1.2 respectively, and >100000 pM for hKV1.5, mKV1.7, hKV3.1, rKV3.4 and hKCa4) . Suppresses T cell activation in vitro (IC50 < 500 pM) .

  • Target

    Potassium Channel

  • Related Pathways

    Membrane transporter/Ion channel

  • CAS Number

    220351

  • Molecular Formula

    C166H268N54O48S7

  • Molecular Weight

    4012.7

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Peptide