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ShK-Dap22 - CAS 220384-25-8
ShK-Dap22 - CAS 220384-25-8
SKU:MF-0153906
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$1,181.97 USD
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$1,181.97 USD
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Product Details
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Bioactivity
Extremely potent KV1.3 channel blocker (Kd = 23 pM for mKV1.3 currents) . Selective for KV1.3 over other mammalian potassium channels (IC50 values are 23, 1800, 10500, 37000 and 39000 pM for mKV1.3, mKV1.1, hKV1.6, mKV1.4 and rKV1.2 respectively, and >100000 pM for hKV1.5, mKV1.7, hKV3.1, rKV3.4 and hKCa4) . Suppresses T cell activation in vitro (IC50 < 500 pM) .
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Target
Potassium Channel
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Related Pathways
Membrane transporter/Ion channel
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CAS Number
220351
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Molecular Formula
C166H268N54O48S7
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Molecular Weight
4012.7
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Peptide