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ShK toxin - CAS 172450-46-3
ShK toxin - CAS 172450-46-3
SKU:MF-0157653-01
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Product Details
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Bioactivity
ShK toxin, isolated from the Caribbean sea anemone (Stichodactyla helianthus), is an inhibitor of the voltage-dependent potassium channel (Kv1.3 channel) . It competes with dendrotoxin I and α-dendrotoxin in binding to rat brain synaptosomal membranes and promotes acetylcholine release. Additionally, ShK toxin reduces K+ currents in cultured rat dorsal root ganglion neurons and inhibits T lymphocyte proliferation [1] [2].
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Target
Potassium Channel
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Related Pathways
Membrane transporter/Ion channel
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CAS Number
172401
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Molecular Formula
C169H274N54O48S7
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Molecular Weight
4054.8
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Peptide