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Molfinity

SHP099 - CAS 1801747-42-1

SHP099 - CAS 1801747-42-1

MF-0015574-01

$33.17 USD
$33.17 USD
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Product Details

  • Bioactivity

    SHP099 (SHP099 free base) free base is an effective, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM) . SHP099 shows dose-dependent pathway inhibition and antitumor activity in xenograft models.

  • Target

    PERK, Phosphatase

  • Related Pathways

    Apoptosis, Metabolism

  • CAS Number

    1801704

  • Purity

    0.994

  • Molecular Formula

    C16H19Cl2N5

  • Molecular Weight

    352.26

  • SMILES

    CC1(N)CCN(CC1)c1cnc(c(N)n1)-c1cccc(Cl)c1Cl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound