SHP2-IN-22 - CAS 2802453-88-7

SHP2-IN-22, a potent SHP2 allosteric inhibitor, exhibits an IC50 value of 17.7 nM and effectively suppresses proliferation, migration, and invasion in MIA PaCa-2 pancreatic cancer cells. This compound is utilized in the study of Kirsten rat sarcoma viral oncogene (KRAS) mutant cancer research [1].

Ras, Others, Phosphatase, Kras

Others, MAPK, Metabolism

2802358

C23H22Cl2N8O

497.38

NC=1C(=NC=C(N1)N2CCN(C(NC3=CC(OC)=C(C#N)C=C3)=N)CC2)C4=C(Cl)C(Cl)=CC=C4

-20°C

Ice Packs

Small Compound