SHP2 protein degrader-2 - CAS 2740582-16-3

SHP2 protein degrader-2 (SHP2-D26), a PROTAC degrader targeting the SHP2 protein, effectively reduces its expression across various cancer cell types [1].

Phosphatase, PROTACs

Metabolism, PROTAC

2740563

C56H79ClN12O6S2

1115.89

C[C@@H](NC(=O)[C@H]1C[C@H](O)CN1C(=O)[C@H](NC(=O)CCCCCCCCN1CCN(CC1)C(=O)CCC(=O)Nc1cccc(Sc2ncc(nc2N)N2CCC(C)(N)CC2)c1Cl)C(C)(C)C)c1ccc(cc1)-c1scnc1C

-20°C

Ice Packs

PROTAC