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SHR0302 - CAS 1445987-21-2
SHR0302 - CAS 1445987-21-2
SKU:MF-0093678-01
Regular price
$64.57 USD
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$64.57 USD
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Product Details
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Bioactivity
SHR0302 (ARQ252) is a JAK inhibitor that binds JAK1 with stronger affinity than others (Selectivity for JAK1 is more than 10 times for JAK2, 77 times for JAK3, 420 times for Tyk2) .
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Target
JAK, Apoptosis
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Related Pathways
Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, JAK/STAT signaling, Apoptosis, Stem Cells, Angiogenesis
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CAS Number
1445964
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Purity
0.9911
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Molecular Formula
C18H22N8O2S
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Molecular Weight
414.48
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SMILES
[H][C@@]12C[C@H](C[C@]1([H])CN(C2)C(=O)Nc1nc(OC)ns1)N(C)c1ncnc2[nH]ccc12
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound