SI-2 - CAS 223788-33-8

SI-2 is an inhibitor (SMI) of steroid receptor coactivator-3 (SRC-3 or AIB1) . SI-2 can selectively reduce the transcriptional activities and the protein concentrations of SRC-3 in cells, and selectively induce breast cancer cell death with IC50 values in the low nanomolar range (3-20 nM), but not affect normal cell viability.

Others, Apoptosis, Src

Apoptosis, Tyrosine Kinase/Adaptors, Others, Angiogenesis

223747

0.984

C15H15N5

265.31

CN1C=2C(N=C1NN=C(C)C3=CC=CC=N3)=CC=CC2

-20°C

Ice Packs

Small Compound