Si306 - CAS 1640012-88-9

Si306, an Src inhibitor, exhibits antitumor activity by reducing the phosphorylation of focal adhesion kinase (FAK) and the expression of epidermal growth factor receptor (EGFR), thereby inhibiting the invasion of human glioblastoma (GBM) .

Src, FAK, EGFR

Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling

1640012-88-9

C25H26BrClN6OS

573.94

ClC(C=1C=CC=CC1)CN2N=CC=3C(=NC(=NC32)SCCN4CCOCC4)NC=5C=CC=C(Br)C5

-20°C

Ice Packs

Small Compound