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Sibenadet - CAS 154189-40-9

Sibenadet - CAS 154189-40-9

SKU:MF-0115366-01

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  • Bioactivity

    Sibenadet (AR-C68397AA (free base) ) is a dual dopamine D2/β2-adrenoceptor agonist with selectivity for β2-adrenoceptor activation. It inhibits capsaicin-induced plasma protein extravasation in rat trachea and reduces edema by activating β2-adrenergic receptors, thereby inhibiting the activation of sensory nerve fibers. Sibenadet is a potential candidate for chronic obstructive pulmonary disease (COPD) research.

  • Target

    Dopamine Receptor, Adrenergic Receptor

  • Related Pathways

    Neuroscience, GPCR/G Protein

  • CAS Number

    154140

  • Molecular Formula

    C22H28N2O5S2

  • Molecular Weight

    464.6

  • SMILES

    O=C1SC=2C(=CC=C(O)C2N1)CCNCCS(=O)(=O)CCCOCCC=3C=CC=CC3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound