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SIC-19 - CAS 713112-69-7
SIC-19 - CAS 713112-69-7
SKU:MF-0148133-01
Regular price
$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
SIC-19, a SIK2 inhibitor, functions by promoting the degradation of SIK2 protein via the ubiquitination pathway. It inhibits the growth of cancer cells and sensitizes cells, ovarian cancer organoids, and xenograft models to PARP inhibitors (such as Olaparib) .
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Target
SIK
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Related Pathways
PI3K/Akt/mTOR signaling
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CAS Number
713112-69-7
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Molecular Formula
C29H26N4O5S2
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Molecular Weight
574.67
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SMILES
O=C(NC(=S)NNC(=O)C1=C(SC(=C1C2=CC=C(OC)C(OC)=C2)C)NC(=O)C=3C=CC=CC3)C=4C=CC=CC4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound