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Sigma-1 receptor antagonist 3 - CAS 1639220-17-9

Sigma-1 receptor antagonist 3 - CAS 1639220-17-9

SKU:MF-0028576-01

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  • Bioactivity

    Sigma-1 receptor antagonist 3 is a more potent and selective antagonist of Sigma-1 (σ1) receptor (Ki = 1.14 nM) than σ2 receptor (Ki = 1239 nM) . Sigma-1 receptor antagonist 3 inhibits Human Ether-a-go-go-Related Gene (hERG, IC50 = 1.54 μM)

  • Target

    Potassium Channel, Sigma receptor

  • Related Pathways

    GPCR/G Protein, Membrane transporter/Ion channel

  • CAS Number

    1639194

  • Purity

    >99.99%

  • Molecular Formula

    C19H23ClFN3O

  • Molecular Weight

    363.86

  • SMILES

    Cc1nc(nc(OCCCN2CCCCC2)c1Cl)-c1ccc(F)cc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound