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Molfinity

Siguazodan - CAS 115344-47-3

Siguazodan - CAS 115344-47-3

SKU:MF-0018844-01

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  • Bioactivity

    Siguazodan (SKF 94836) is an effective, selective, orally active phosphodiesterase III ((PDE-III) ) inhibitor with an IC50 of 117 nM. Siguazodan inhibited phenylephrine induced 5-HT release with an IC50 value of 4.2 μM. Siguazodan can increase cAMP accumulation in intact platelets, with EC50 of 18.88 μM.

  • Target

    PDE

  • Related Pathways

    Metabolism

  • CAS Number

    115294

  • Purity

    0.9987

  • Molecular Formula

    C14H16N6O

  • Molecular Weight

    284.32

  • SMILES

    CN\C(NC#N)=N/c1ccc(cc1)C1=NNC(=O)CC1C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound