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Siguazodan - CAS 115344-47-3
Siguazodan - CAS 115344-47-3
SKU:MF-0018844-01
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$35.41 USD
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Product Details
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Bioactivity
Siguazodan (SKF 94836) is an effective, selective, orally active phosphodiesterase III ((PDE-III) ) inhibitor with an IC50 of 117 nM. Siguazodan inhibited phenylephrine induced 5-HT release with an IC50 value of 4.2 μM. Siguazodan can increase cAMP accumulation in intact platelets, with EC50 of 18.88 μM.
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Target
PDE
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Related Pathways
Metabolism
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CAS Number
115294
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Purity
0.9987
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Molecular Formula
C14H16N6O
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Molecular Weight
284.32
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SMILES
CN\C(NC#N)=N/c1ccc(cc1)C1=NNC(=O)CC1C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound