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SIK2/3-IN-1 - CAS 3038863-24-7

SIK2/3-IN-1 - CAS 3038863-24-7

MF-0114649-01

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Product Details

  • Bioactivity

    SIK2/3-IN-1 (Compound 7S) is an orally active and selective inhibitor of SIK2/3. It significantly inhibits tumor growth without causing weight loss in the MV4-11 AML mouse CDX model. SIK2/3-IN-1 is applicable for research in MEF2C-dependent acute myeloid leukemia.

  • Target

    SIK

  • Related Pathways

    PI3K/Akt/mTOR signaling

  • CAS Number

    3038832

  • Molecular Formula

    C20H19F3N6O2

  • Molecular Weight

    432.399

  • SMILES

    O=C1C=2C(=NC(=CC2CCN1CC(F)(F)F)C=3C=C(C=NC3N)C=4C=NN(C4)C)OC

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound