Molfinity
Silybin B - CAS 142797-34-0
Silybin B - CAS 142797-34-0
SKU:MF-0093159-01
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Product Details
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Bioactivity
Silybin B (Silibinin B) is an effective inhibitor of raloxifene 4 '- and 6-glucosalylation, an effective anti-fibrinogenic and anti-oligomeric component of Silymarin, with free radical scavenging activity of 1, 1-diphenyl-2-pyridinyl hydrazine (DPPH), and a protective effect against cisplatin-induced neurotoxicity by alleviating DNA damage and apoptosis. Silybin B can inhibit the growth of human chronic myeloid leukemia K562 cells and induce apoptosis.
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Target
Bcr-Abl, p38 MAPK, Apoptosis, Beta Amyloid, JNK
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Related Pathways
Angiogenesis, Cytoskeletal Signaling, MAPK, Neuroscience, Apoptosis, Tyrosine Kinase/Adaptors
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CAS Number
142763
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Purity
0.9999
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Molecular Formula
C25H22O10
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Molecular Weight
482.44
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SMILES
COc1cc(ccc1O)[C@@H]1Oc2cc(ccc2O[C@H]1CO)[C@H]1Oc2cc(O)cc(O)c2C(=O)[C@@H]1O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product