Simepdekinra - CAS 2978700-29-5

Simepdekinra (Compound 221) is a potent IL-17A modulator with IC50 values ≤10 nM for IL-17A/A HEK-Blue cells and 10–100 nM for IL-17A/F HEK-Blue cells, suitable for studying psoriasis, ankylosing spondylitis, and psoriatic arthritis.

IL Receptor

Immunology/Inflammation

2978666

C35H50FN7O5

667.81

[C@H]([C@H](NC(=O)C=1N(CC)N=CC1)C(NC2=C(F)C=C([C@@H]([C@H](C(=O)N3C[C@@H](C)N(C)CC3)NC([C@@H](OC)C)=O)C)C=C2)=O)(C4CC4)C5CC5

-20°C

Ice Packs

Small Compound