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Simotinib hydrochloride - CAS 1538617-88-7

Simotinib hydrochloride - CAS 1538617-88-7

MF-0152639

$901.17 USD
$901.17 USD
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Product Details

  • Bioactivity

    Simotinib hydrochloride is a selective and orally bioavailable EGFR tyrosine kinase inhibitor, showing strong specificity with an IC 50 of 19.9 nM. This compound exhibits potent antineoplastic activities.

  • Target

    Others, EGFR

  • Related Pathways

    Others, Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors

  • CAS Number

    1538522

  • Molecular Formula

    C25H27Cl2FN4O4

  • Molecular Weight

    537.41

  • SMILES

    Cl.COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCN1CC2(CC2)C2(C1)OCCO2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound