SIMR3030 - CAS 2708270-99-7

SIMR3030, a potent inhibitor of SARS-CoV-2 PLpro, possesses an IC50 of 0.0399 μg/mL and demonstrates antiviral activity by diminishing the expression of SARS-CoV spike, ORF1b, IFN-α, and IL-6 mRNA. Additionally, SIMR3030 has been shown to have a satisfactory safety profile in mice [1].

SARS-CoV

Microbiology/Virology

2708164

C27H29N3O2

427.54

O(C)[C@]12[C@](N3[C@@](CC1)(C4=C(CC3)C=5C(N4)=CC=CC5)[H])(CC6=C(C2)C=7C(N6)=CC=C(OC)C7)[H]

-20°C

Ice Packs

Small Compound