Sinapinic Acid - CAS 530-59-6

Sinapinic Acid (Synapoic acid) protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p65 activation and proinflammatory cytokine expression. Sinapic acid with antioxidant role protects cardiac cells and its functions from I/R induced oxidative stress. Sinapic acid is a potentially useful agent for the protection against liver fibrosis and cirrhosis. Sinapic acid prevents the alterations in the levels of lipids and lipoproteins by virtue of its anti-lipidaemic effect in isoproterenol induced myocardial infarcted rats. Sinapic acid ameliorates hyperglycemia through PLC-PKC signals to enhance the glucose utilization in diabetic rats.

HDAC, RAAS, Angiotensin-converting Enzyme (ACE), Reactive Oxygen Species, Apoptosis, ROS

Endocrinology/Hormones, NF-κB, Chromatin/Epigenetic, Apoptosis, DNA Damage/DNA Repair, Metabolism, Immunology/Inflammation

465

>99.99%

C11H12O5

224.21

O(C)C1=C(O)C(OC)=CC(C=CC(O)=O)=C1

-20°C

Ice Packs

Natural Product