SIQ17 - CAS 2151881-74-0

SIQ17, an EGFR inhibitor, blocks the ATP-binding site with an IC50 of 0.62 nM, demonstrating more effective EGFR-TK inhibitory activity than the known inhibitor Erlotinib (IC50 of ∼20 nM) . SIQ17 is applicable in cancer research [1].

EGFR

Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors

2151881-74-0

C32H27NO2S

489.63

S(=O)(=O)(C1=C2C(C=3C1=CC=CC3)=C(N(C)C=4C2=CC=CC4)C5=C(C)C=C(C)C=C5)C6=CC=C(C)C=C6

-20°C

Ice Packs

Small Compound