SIRT1/2/3-IN-1 - CAS 2413212-06-1

SIRT1/2/3-IN-1 (compound 10) is a potent, selective, and cell-permeable inhibitor targeting SIRT1, SIRT2, and SIRT3, with inhibitory concentrations (IC50s) of 0.54 μM, 0.253 μM, and 0.72 μM, respectively. It is utilized in cancer research [1].

Sirtuin, Others

Chromatin/Epigenetic, Others, DNA Damage/DNA Repair

2413212-06-1

C46H63N9O8S2

934.18

C(N[C@H](C(N[C@H]1CC=2C=CC(=CC2)OCCCCCNC(=O)[C@H](CCSC)NC1=O)=O)CCCCNC(C)=S)(=O)[C@@H]3CC=4C=CC(=CC4)OCCCC(=O)N[C@@H](CC5=CN=CN5)C(=O)N3

-20°C

Ice Packs

Small Compound