Sirt1/2-IN-1 - CAS 2402779-21-7

Sirt1/2-IN-1 (Compound 7) is an inhibitor of SIRT1 and SIRT2, with IC50 values of 1.81 μg/mL for SIRT1, 2.10 μg/mL for SIRT2, and 20.5 μg/mL for SIRT3, and exhibits α-microtubulin hyperacetylation activity, demonstrating significant anticancer effects.

Others, Sirtuin, Microtubule Associated

Chromatin/Epigenetic, DNA Damage/DNA Repair, Cytoskeletal Signaling, Others

2402751

C22H13ClN2OS2

420.93

O=C1N2C(C3=C(C=4C(S3)=CC=C(Cl)C4)N=C2SC1)C5=CC6=C(C=C5)C=CC=C6

-20°C

Ice Packs

Small Compound